Taprenepag isopropyl

SKU: orb1706582

Description

Taprenepag isopropyl

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1005549-94-9
• MW: 520.6
• Purity: 99.44%
• Formula: C₂₇H₂₈N₄O₅S
• SMILES: CC(C)OC(=O)COc1cccc(CN(Cc2ccc(cc2)-n2cccn2)S(=O)(=O)c2cccnc2)c1
• Target: Prostaglandin Receptor
• Solubility: DMSO:160 mg/mL (307.34 mM);10% DMSO+90% Corn Oil:5 mg/mL (9.6 mM)

Bioactivity

• In Vivo:
  Taprenepag isopropyl (0.75, 12, or 36 μg/day, instilled into the right eye twice daily for 28 days) demonstrated intraocular pressure-lowering effects in cynomolgus monkeys but also induced adverse reactions such as iritis, photophobia, and increased corneal thickness. These adverse reactions were reversible after discontinuation of the drug .

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Taprenepag isopropyl, ProstaglandinReceptor, Prostaglandin Receptor, PF 04217329, PF04217329, PF-04217329, EP2 Receptor

Compound Identifiers

PubChem CID

23729077