Tandutinib hydrochloride

SKU: orb1908984

Description

Tandutinib hydrochloride (MLN518 hydrochloride) is a potent, selective FLT3 inhibitor with an IC50 of 0.22 μM and also effectively inhibits c-Kit and PDGFR, with IC50 values of 0.17 μM and 0.20 μM, respectively. This compound is clinically applicable for treating acute myelogenous leukemia (AML) and can cross the blood-brain barrier.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2438900-70-8
MW	599.16
Formula	C₃₁H₄₃ClN₆O₄
SMILES	O(C)C1=CC=2C(=NC=NC2C=C1OCCCN3CCCCC3)N4CCN(C(NC5=CC=C(OC(C)C)C=C5)=O)CC4.Cl
Target	Apoptosis,Others,PDGFR,c-Kit,FLT

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

138911453 ↗

Key Properties

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No computed properties available.

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