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Description

TAME is a cell-permeable inhibitor of the Anaphase-Promoting Complex/Cyclosome (APC/C). It functions by competitively blocking the binding of the activators Cdc20 and Cdh1, thereby inhibiting APC/C-dependent proteolysis. This compound is a valuable tool for studying cell cycle regulation, mitotic exit, and aneuploidy in both cellular and biochemical assays.

Research Area

Cell Biology

Images & Validation

Key Properties

TargetAPC/C
CAS Number901-47-3
MW342.41
FormulaC14H22N4O4S
SMILESS(N[C@@H](CCCNC(=N)N)C(OC)=O)(=O)(=O)C1=CC=C(C)C=C1

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Tosyl-Arginine Methyl Este, Tosylarginine methyl ester, TAME, APC, Anaphase promoting complex, N-4-Tosyl-L-arginine methyl ester

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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TAME (orb1685626)

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Available Sizes

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5 mg
$ 70.00
1 ml x 10 mM (in DMSO)
$ 90.00
DispatchUsually dispatched within 5-10 working days
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