TAM558 intermediate-5

SKU: orb2663885

Description

TAM558intermediate-54 is a synthetic precursor to the cytotoxic payload TAM558, which is conjugated to the anti-FAP antibody in OMTX705. This antibody-drug conjugate demonstrates antitumor activity in preclinical research, including in vitro cytotoxicity assays and in vivo xenograft models targeting fibroblast activation protein-expressing tumors.

Key Properties

• CAS Number: 1415659-15-2
• MW: 772.05
• Formula: C₄₁H₆₅N₅O₇S
• SMILES: [C@H](C[C@@H](N(C([C@@H](NC(=O)[C@@H]1N(C)CCCC1)[C@H](CC)C)=O)CCC)[C@@H](C)C)(OCCC)C2=NC(C(N[C@@H](CC3=CC=C(O)C=C3)C[C@@H](C(O)=O)C)=O)=CS2
• Target: ADC Cytotoxin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

89520284