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Catalog Number | orb1299877 |
---|---|
Category | Small Molecules |
Description | Talarozole |
CAS Number | 201410-53-9 |
Purity | 98% |
MW | 377.51 |
SMILES | CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 |
Formula | C21H23N5S |
Biological Activity | Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively.Talarozole for the treatment of acne, psoriasis and other keratinization disorders. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |