Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Talarozole

SKU: orb1299877

Description

Talarozole (R115866) is an orally active RAMBA that potently inhibits CYP26A1 and CYP26B1, enzymes which catabolize retinoic acid. This inhibition elevates endogenous retinoid levels, underpinning its research use in models of acne, psoriasis, and related dermatological disorders.

Research Area

Cell Biology, Metabolism Research

Images & Validation

Key Properties

CAS Number201410-53-9
MW377.51
Purity98.00% (May vary between batches)
FormulaC21H23N5S
SMILESCCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
TargetCytochromes P450,Autophagy,Retinoid Receptor
SolubilityDMSO:36 mg/mL (95.36 mM);10% DMSO+90% Corn Oil:2 mg/mL (5.3 mM)

Bioactivity

Target IC50
CYP26B1/A1:0.46/5.1 nM (IC50)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Autophagy, CYPs, CYP, Cytochrome P450, inhibit, Inhibitor, Talarozole, Retinoid Receptor, Retinoid X receptors, RetinoidReceptor, Retinoic acid receptors, R 115866, R115866, R-115866, RAMBA, RAR/RXR

Similar Products

  • Talarozole (R enantiomer) [orb1708154]

    870093-23-5

    377.51

    C21H23N5S

    50 mg, 100 mg, 25 mg
  • (-)-Talarozole [orb1708155]

    201410-67-5

    377.51

    C21H23N5S

    50 mg, 100 mg, 25 mg
  • Talarozole [orb1220458]

    >98% (HPLC)

    201410-53-9

    377.51

    C21H23N5S

    2 mg, 5 mg, 10 mg, 50 mg, 100 mg, 25 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 180.00
1 ml x 10 mM (in DMSO)
$ 190.00
10 mg
$ 220.00
25 mg
$ 290.00
50 mg
$ 370.00
100 mg
$ 530.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry