TAK-960 dihydrochloride

SKU: orb1745011

Description

TAK-960 dihydrochloride is a potent and selective oral PLK1 inhibitor (IC50 = 0.8 nM) with additional activity against PLK2 and PLK3. It demonstrates robust anti-proliferative effects in diverse cancer cell lines in vitro and shows significant efficacy in tumor xenograft models in vivo, supporting its use in oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• MW: 634.52
• Formula: C₂₇H₃₆Cl₂F₃N₇O₃
• SMILES: CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2F)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC.Cl.Cl
• Target: Others,PLK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

129626435