TAK-653

SKU: orb1688517

Description

TAK-653 is a selective AMPA receptor positive allosteric modulator with negligible intrinsic agonist activity. It demonstrates antidepressant-like efficacy in rodent models and has shown a promising preclinical safety profile, supporting its investigation for mood disorder research.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1358751-06-0
• MW: 373.47
• Purity: 99.89% (May vary between batches)
• Formula: C₁₉H₂₃N₃O₃S
• SMILES: CC1=CN2CCS(=O)(=O)N=C2C(=N1)c1ccc(OC2CCCCC2)cc1
• Target: iGluR,Lipoxygenase
• Solubility: DMSO:11.7 mg/mL (31.33 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AMPAR

Compound Identifiers

PubChem CID

56655833