Tabernanthalog

SKU: orb1689772

Description

Tabernanthalog (TBG) is a 5-HT2A receptor agonist. Research in rodent models demonstrates its potential to induce neuroplasticity, decrease addictive behaviors for substances like alcohol and heroin, and exhibit antidepressant-like activity, supporting its study in neuroscience and psychiatry.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2483829-58-7
• MW: 230.31
• Purity: 99.82%
• Formula: C₁₄H₁₈N₂O
• SMILES: O(C)C=1C=C2C(C3=C(N2)CCN(C)CC3)=CC1
• Target: 5-HT Receptor
• Solubility: DMSO: 100 mg/mL (434.2 mM), sonication is recommended.

Bioactivity

• In Vivo:
  After 7 days of unpredictable mild stress (UMS) in mice, immobility time was significantly increased after UMS. This effect was rescued by a 50 mg/kg, but not 10 mg/kg, dose of Tabernanthalog.

Storage & Handling

• Storage: store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

5HT Receptor, 5HTReceptor, 5-HT2A, TBG, Tabernanthalog

Compound Identifiers

PubChem CID

146026994