TA-02

SKU: orb1302685

Description

TA-02 is a potent and selective p38 MAPK inhibitor (IC50 = 20 nM) that also demonstrates activity against TGFBR-2. This small molecule is a valuable research tool for investigating inflammatory pathways, fibrosis, and cancer biology in both cellular and animal models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1784751-19-4
• MW: 333.33
• Purity: 99.78%
• Formula: C₂₀H₁₃F₂N₃
• SMILES: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccccc1F
• Target: Autophagy,p38 MAPK
• Solubility: DMSO:50 mg/mL (150 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6 mM)

Bioactivity

• Target IC50:
  p38 MAPK:20 nM

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX-2, DMPK2, CIT, CK1ε, Autophagy, BDNF, DDR1 CK1δ, LEF-1, MEK5, Inhibitor, inhibit, JNK2, JNK3, JNK1, p38 MAPK, p38MAPK, TA02, TA-02, TA 02, TCF

Compound Identifiers

PubChem CID

91691130