T521

SKU: orb1699192

Description

T521 is a potent and selective small-molecule inhibitor targeting the Polo-box domain (PBD) of Plk1, exhibiting high specificity over Plk2 and Plk3. It is a valuable research tool for studying mitotic progression and has been utilized in both in vitro and in vivo cancer research models to investigate Plk1-dependent pathways.

Research Area

Cell Biology, Protein Biochemistry

Key Properties

• CAS Number: 891020-54-5
• MW: 395.43
• Purity: 99.71% (May vary between batches)
• Formula: C₁₇H₁₄FNO₅S₂
• SMILES: S(=O)(=O)(C1=C(S(CC)(=O)=O)OC(=N1)C2=CC=C(F)C=C2)C3=CC=CC=C3
• Target: E1/E2/E3 Enzyme,PLK
• Solubility: DMSO:45 mg/mL (113.8 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

T 521, T521, T-521, PLK1

Compound Identifiers

PubChem CID

16013351