T2AA hydrochloride

SKU: orb2282964

Description

T2AA is a small molecule PCNA inhibitor that disrupts PCNA's interactions with partner proteins like p21, leading to replication inhibition, S-phase arrest, and sensitization to cisplatin-induced DNA damage. It is a valuable research tool for studying DNA replication, repair mechanisms, and combination therapies in cancer cell models like HeLa and U2OS.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2138331-07-2
• MW: 547.6
• Formula: C₁₅H₁₅I₂NO₃?HCl
• SMILES: O(C1=C(I)C=C(C[C@@H](CO)N)C=C1I)C2=CC=C(O)C=C2.Cl
• Target: DNA/RNA Synthesis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

91885407