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SZU305

SKU: orb3211155

Description

SZU305 is a RAD51 PROTAC degrader with DC50 values of 307.45 nM and 84.19 nM in SK-HEP-1 and Huh-7 cell lines, respectively. It inhibits DNA damage repair, induces cell cycle arrest, and triggers apoptosis (apoptosis). At high concentrations, SZU305 moderately reduces the protein levels of IKZF1 and IKZF3. This compound is applicable in hepatocellular carcinoma research.

Images & Validation

Key Properties

TargetDNA/RNA Synthesis,IKZF,PROTACs,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information