Swertiajaponin

SKU: orb1684191

Description

Swertiajaponin

Research Area

Immunology & Inflammation, Protein Biochemistry

Key Properties

• CAS Number: 6980-25-2
• MW: 462.4
• Purity: 99.92%
• Formula: C₂₂H₂₂O₁₁
• SMILES: COc1cc2oc(cc(=O)c2c(O)c1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)-c1ccc(O)c(O)c1
• Target: Tyrosinase,ROS

Bioactivity

• Target IC50:
  Tyrosinase:43.47 μM
• In Vitro:
  Isolated LDL was incubated with compounds 1-3 and the kinetics of lipid peroxidation were assessed by conjugated diene and malondialdehyde-thiobarbituric acid reactive substances (MDA-TBARS) formation after addition of copper ions. Significant differences (p < 0.05) between the lag time phase of the control and the lag time phase in the presence of the compounds 1 (0.25 microM) and 2 (0.50 microM) were observed. After five hours of incubation all three compounds showed a significant inhibitory effect on MDA-TBARS formation with respect to the control. After six hours of incubation only compound 1 kept a remarkable antioxidant effect

Storage & Handling

• Storage: store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

tyrosinase, Tyrosinase, Swertiajaponin, Antifection, inhibit, Inhibitor

Compound Identifiers

PubChem CID

442659