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SW157765

SKU: orb2900926

Description

SW157765 is a selective non-canonical glucose transporter GLUT8 (SLC2A8) inhibitor. KRAS/KEAP1 double mutant NSCLC cells are selectively sensitive to the SW157765, due to the convergent consequences of dual KRAS and NRF2 modulation of metabolic and xenobiotic gene regulatory programs.

Images & Validation

Key Properties

CAS Number332063-87-3
MW331.32
Purity>98% (HPLC)
FormulaC19H13N3O3
SMILESO=C(Nc1ccc2oc(nc2c1)-c1ccncc1)\C=C\c1ccco1
SolubilityIn Vitro: DMSO : 25 mg/mL (75.46 mM; Ultrasonic (<60°C)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information