SV119 hydrochloride

SKU: orb3174578

Description

SV119 hydrochloride is a sigma-2 ligand with a Ki value of 5.2 nM. It enhances the efficient transport of drugs across cancer cell membranes. Combining dm-Erastin with SV119 hydrochloride successfully overcomes internalization barriers observed in pancreatic cancer while retaining the inherent antitumor activity of Erastin. Additionally, SV119 hydrochloride exhibits cytotoxic effects on triple-negative breast cancer (TNBC) cells and induces apoptosis (apoptosis).

Key Properties

• CAS Number: 913816-12-3
• MW: 476.48
• Formula: C₂₃H₃₉Cl₂N₃O₃
• SMILES: NCCCCCCN1[C@]2([H])C[C@H](C[C@@]1([H])CCC2)OC(NC3=C(C=CC(C)=C3)OC)=O.Cl.Cl
• Target: Sigma receptor,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Sigma receptor,Apoptosis