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Suvorexant

SKU: orb1941118

Description

A potent, CNS penetrant, orally available, dual orexin receptor antagonist with Ki of 0.55 and 0.35 nM for OX1R and OX2R, respectively; significantly and dose-dependently reduces locomotor activity and promotes sleep in rats.Sleep Disorder Launched.

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Key Properties

CAS Number1030377-33-3
MW450.92
Purity>98% (HPLC)
FormulaC23H23ClN6O2
SMILESO=C(N1CCN(C2=NC3=CC(Cl)=CC=C3O2)CC[C@H]1C)C4=CC(C)=CC=C4N5N=CC=N5
TargetOrexin Receptor
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

MK-4305

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Suvorexant (orb1941118)

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