Suprafenacine

SKU: orb1304885

Description

Suprafenacine is a cell-permeable small molecule that destabilizes microtubules by binding at the colchicine site, leading to G2/M phase arrest and apoptosis. It demonstrates selective activity against various cancer cell lines, including those with drug-resistant phenotypes, making it a useful research tool for studying mitotic disruption and anticancer mechanisms in vitro.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1477482-50-0
• MW: 282.34
• Purity: 99.91% (May vary between batches)
• Formula: C₁₆H₁₈N₄O
• SMILES: CC1=CC=C(\C=N\NC(=O)C2=NNC3=C2CCCC3)C=C1
• Target: Microtubule Associated
• Solubility: DMSO:2.83 mg/mL (10.02 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Suprafenacine, N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide, microtubule, MicrotubuleAssociated, Microtubule Associated

Compound Identifiers

PubChem CID

6861947