Sumanirole maleate

SKU: orb1679041

Description

Sumanirole maleate (PNU-95666E) is a selective, high-affinity dopamine D2 receptor full agonist (ED50 = 46 nM). It has been utilized in research models of Parkinson's disease to study motor improvement and is a compound of interest for investigating the pathophysiology of restless legs syndrome.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 179386-44-8
• MW: 319.31
• Formula: C₁₅H₁₇N₃O₅
• SMILES: C(=C\C(O)=O)\C(O)=O.O=C1N2C3=C(C[C@@H](NC)C2)C=CC=C3N1
• Target: Dopamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.26 mM);DMSO:40 mg/mL (125.27 mM);H2O:8 mg/mL (25.05 mM)

Bioactivity

• Target IC50:
  D2 receptor:46 nM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Sumanirole Maleate, PNU-95666, PNU95666, PNU 95666, U95666E, U-95666E, DopamineReceptor, Dopamine Receptor, D2

Compound Identifiers

PubChem CID

9818478