Sulfaphenazole

SKU: orb1302751

Description

Sulfaphenazole is a potent and selective CYP2C9 inhibitor (Ki: 0.3 µM) with over 100-fold selectivity against other major CYPs. It is used in vitro and in vivo to study CYP2C9's role in drug metabolism and has been applied in vascular research to investigate endothelial CYP-mediated oxidative signaling and vascular tone regulation.

Research Area

Cell Biology, Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 526-08-9
• MW: 314.36
• Purity: 99.97% (May vary between batches)
• Formula: C₁₅H₁₄N₄O₂S
• SMILES: NC1=CC=C(C=C1)S(=O)(=O)NC1=CC=NN1C1=CC=CC=C1
• Target: Cytochromes P450,Necroptosis,Antibiotic,Antibacterial,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.36 mM);Ethanol:0.5 mg/mL (1.59 mM);DMSO:50 mg/mL (159.05 mM)

Bioactivity

• Target IC50:
  CYP2C9:0.3 μM (Ki)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Depotsulfonamide, Depocid, CYP2C9, Bacterial, Inhibitor, Plisulfan, inhibit, Raziosulfa, Sulfaphenazole

Compound Identifiers

PubChem CID

5335