Succinate/succinate receptor antagonist 1

SKU: orb1745217

Description

Succinate/succinate receptor antagonist 1 is a potent small molecule inhibitor of the succinate receptor (SUCNR1/GPR91) with an IC50 of 20 µM. It blocks succinate-mediated signaling and is a valuable research tool for studying metabolic inflammation in periodontal disease models, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2361972-29-2
• MW: 277.32
• Purity: 99.53% (May vary between batches)
• Formula: C₁₇H₁₅N₃O
• SMILES: CNC(=O)Cc1ccc(cc1)-c1ccc2cccnc2n1
• Target: Succinate Receptor 1 (SUCNR1),Others
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.61 mM);DMSO:5 mg/mL (18.03 mM)

Bioactivity

• Target IC50:
  SUCNR1:20 µM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Argininosuccinate synthase, Succinate/succinate receptor antagonist 1, Succinate/succinatereceptorantagonist1

Compound Identifiers

PubChem CID

139308923