Streptomycin sulfate

SKU: orb1310981

Description

Streptomycin sulfate

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 3810-74-0
• MW: 728.68
• Purity: 99.86%
• Formula: C₂₁H₃₉N₇O₁₂·3/2H₂SO₄
• SMILES: N=C(N)N[C@@H]([C@@H]([C@H]([C@@H]([C@H]1O)O)NC(N)=N)O)[C@H]1O[C@H](O[C@H]([C@]2(O)C=O)C)[C@@H]2O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC.O=S(O)(O)=O
• Target: Antibacterial,Antibiotic,ribosome
• Solubility: H2O:242.5 mg/mL (332.79 mM);DMSO:Insoluble

Bioactivity

• In Vitro:
  Strain RB1 exhibits an increased susceptibility to streptomycin that correlates positively with the concentration of CV in the growth medium. Furthermore, as the CV concentration rises, both cytochrome aa3 levels and the bacterium's sensitivity to streptomycin simultaneously escalate. It is noteworthy that cytochrome aa3 plays a critical role in the uptake of streptomycin by B. subtilis. Additionally, streptomycin affects tRNA selection, with resistance mutations predominantly located in protein S12; these mutations are typically associated with enhanced specificity in the tRNA selection process.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Streptomycin, Streptomycin sulfate, Streptomycin Sulfate, Plantomycin, Phytomycin, Bacterial, Antibiotic, 30S ribosome, inhibit, Inhibitor, Estreptomicina

Compound Identifiers

PubChem CID

176525877