STO-609 acetate

SKU: orb1693678

Description

STO-609 acetate is a potent, cell-permeable inhibitor that selectively targets CaM-KKα and CaM-KKβ by competing at their ATP-binding sites. It exhibits high selectivity, showing over 80-fold preference for CaM-KK over several other kinases. This inhibitor is widely used in vitro to study CaM-KK signaling pathways in metabolism, cellular stress, and neuronal function.

Research Area

Cell Biology, Epigenetics & Chromatin, Neuroscience, Signal Transduction

Key Properties

• CAS Number: 1173022-21-3
• MW: 374.35
• Purity: 99.75%
• Formula: C₁₉H₁₀N₂O₃·C₂H₄O₂
• SMILES: CC(=O)O.c1ccc2c(c1)nc1n2c(=O)c2cccc3c(ccc1c23)C(=O)O
• Target: AMPK,Autophagy,CaMK
• Solubility: DMSO:10 mM

Bioactivity

• Target IC50:
  CaMKKβ:15 ng/ml(ki)|CaMKKα:80ng/ml(ki)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CaM-KKα, CaM-KKβ, STO 609 Acetate, STO 609 acetate, STO609 Acetate, STO609 acetate, STO-609 Acetate

Compound Identifiers

PubChem CID

16760660