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STM2457

SKU: orb1218283

Description

STM2457 is a first-in-class, highly potent, selective and orally active inhibitor of METTL3 . It can be used for the research of acute myeloid leukaemia (AML).

Images & Validation

Key Properties

CAS Number2499663-01-1
MW444.53
Purity>98% (HPLC)
FormulaC25H28N6O2
SMILESO=C(C(N=C1N2C=CC=C1)=CC2=O)NCC3=CN4C=C(CNCC5CCCCC5)C=CC4=N3
TargetMETTL3
SolubilityDMSO:125 mg/mL (281.20 mM; Need ultrasonic)

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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  • STM2457 [orb1298402]

    99.42% (May vary between batches)

    2499663-01-1

    444.53

    C25H28N6O2

    1 ml x 10 mM (in DMSO), 1 mg, 5 mg, 10 mg, 25 mg, 50 mg
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Protocol Information

Available Sizes

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500 mg
100 mg
200 mg
5 mg
$ 320.00
10 mg
$ 500.00
25 mg
$ 820.00
50 mg
$ 1,170.00