STING modulator-4

SKU: orb1744788

Description

STING Modulator-4 is a competitive inhibitor of the R232H STING variant with a K_i of 0.0933 µM, though it shows weak activity (EC_50 >10 µM) for p-IRF3 activation in THP-1 cells. This small molecule is a useful research tool for investigating STING signaling and its variants in biochemical and cellular assays.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• CAS Number: 2839639-72-2
• MW: 350.38
• Formula: C₁₇H₁₈N₈O
• SMILES: CN1C(C2=C3C(=CC(C(N)=O)=N2)N(C)N=C3)=NC(=C1)C=4N(CC)N=CC4
• Target: Others,STING

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165170527