STING agonist-50

SKU: orb3210118

Description

STINGagonist-50 is an orally active STING agonist with an IC50 of 3.457 μM. It activates the STING signaling pathway, promoting the phosphorylation of downstream TBK1 and IRF3. Additionally, STINGagonist-50 induces the expression of IFN-β, CXCL10, and IL-6. It inhibits tumor growth in homologous mouse models and is applicable in colorectal cancer research.

Key Properties

• CAS Number: 3058842-90-0
• MW: 395.80
• Formula: C₂₀H₁₄ClN₃O₄
• SMILES: O=C(O)C1=CC(=CC=2C(Cl)=C(OC12)CN3C(=O)C=4C=NN5C=CC=C(C45)C3)C
• Target: Interleukin,IκB/IKK,STING,CXCR,IFNAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,IκB/IKK,STING,CXCR,IFNAR