STING agonist-46

SKU: orb3173319

Description

STINGagonist-46 is an orally active STING agonist that activates the STING signaling pathway, leading to the phosphorylation of TBK1 and IRF3, and enhances the secretion of IFN-β and IP-10. It directly binds to STING, increasing its thermal stability. In B16F10, CT26, and 4T1 mouse models, STINGagonist-46 demonstrates potent antitumor efficacy. This compound can be utilized for research in cancer immunotherapy.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 3033532-05-4
• MW: 351.42
• Formula: C₁₇H₂₁NO₅S
• SMILES: O=C(ONC(C)C)CCC(=O)C=1SC=2C=C(OC)C(OC)=CC2C1
• Target: STING

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STING