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STING agonist-25

SKU: orb1982331

Description

STING agonist-23 (CF505) is a synthetic small molecule that potently activates the STING pathway, leading to TBK1/IRF3 phosphorylation and robust induction of type I interferons and pro-inflammatory cytokines. Its activity, demonstrated in cellular studies, supports its use in immuno-oncology and antiviral research, including against coronaviruses.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number2408723-10-2
MW751.79
FormulaC36H41N13O6
SMILESC(/C=C/CN1C=2C(N=C1NC(=O)C=3N(CC)N=C(C)C3)=CC(C(N)=O)=CN2)N4C=5C(N=C4NC(=O)C=6N(CC)N=C(C)C6)=CC(C(N)=O)=CC5OCCCO
TargetOthers,STING

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information