STING Agonist 12b

• Catalog Number: orb1692259
• Category: Small Molecules
• Description: STING Agonist 12b
• Purity: 98.00%
• MW: 253.3
• Biological Activity: STING agonist 12b is an agonist of stimulator of interferon genes (STING).1It binds to STING (Kd= 26.4 μM) and induces interferon reporter gene expression in cells expressing human or mouse STING (EC50s = 7.45 and 10.23 μM, respectively). STING agonist 12b (40 μM) induces expression of TNF-a, IL-6, IP-10, and IL-1b in THP-1 cells.
• CAS Number: 2411100-70-2
• Formula: C₁₆H₁₅NO₂
• SMILES: O=C1C=2C(NC=3C1=CC=C(C)C3C)=CC=C(OC)C2
• Storage: -20°C
• Note: For research use only