Stellettin B

SKU: orb2663449

Description

Stellettin B is a marine-derived triterpene that inhibits the PI3K/Akt/mTOR pathway, inducing G1 arrest, apoptosis, and autophagy in A549 lung cancer cells. It also suppresses MAPK and FAK signaling to reduce migration and invasion in hepatocellular carcinoma models, making it a valuable tool for anticancer mechanism studies in vitro.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 184885-91-4
• MW: 462.62
• Formula: C₃₀H₃₈O₄
• SMILES: C[C@@]1\2[C@]([C@]3(C)[C@@](CC1)(C(C)(C)C(=O)CC3)[H])(CC(=O)/C2=C(\C=C\C=C(/C)\C=4OC(=O)C(C)=CC4)/C)[H]
• Target: Apoptosis,Autophagy,PI3K,Akt,mTOR,FAK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

5352082