STAT6-IN-9

SKU: orb3218121

Description

STAT6-IN-9 is a highly potent STAT6 inhibitor with an EC₅₀ of 4 nM. It markedly blocks STAT6 activation mediated by the IL-13/IL-13 receptor/IL-4 receptor pathway and inhibits CCL17 secretion with an IC50 of 4.6 nM. STAT6-IN-9 is suitable for studying various chronic inflammatory diseases related to the STAT6 signaling pathway, including allergic diseases, asthma, and chronic obstructive pulmonary disease.

Key Properties

• CAS Number: 3092076-15-5
• MW: 568.67
• Purity: 99.66% (May vary between batches)
• Formula: C₃₁H₃₆N₈O₃
• SMILES: O=C(NCC1=CC=C(C=C1)NC(=O)N2CCN(C)CC2)C3=NN(C4=CC=C(C=C34)C=5N=CC(=CC5)C(=O)N(C)C)CC
• Target: STAT

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

STAT