STAT6-IN-4

SKU: orb2564359

Description

STAT6-IN-4 (Compound 78) is a potent STAT6 inhibitor with an IC50 of 0.34 µM. This small molecule is a valuable research tool for investigating the role of STAT6 signaling in inflammatory and allergic disease models, both in vitro and in vivo.

Research Area

Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 3033742-14-9
• MW: 580.56
• Purity: 99.96% (May vary between batches)
• Formula: C₂₉H₂₇F₃N₆O₄
• SMILES: O=C(NC1=NC(OC)=CC=C1)C2=CC(=CC=3C=C(C4=CC=C(C=C4)N5C(=O)N(N=C5C)C)N(C32)CCOC)C(F)(F)F
• Target: STAT
• Solubility: DMSO:80 mg/mL (137.8 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.68 mM)

Bioactivity

• Target IC50:
  STAT6:0.34 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171714309