STAT6-IN-2

SKU: orb2278141

Description

STAT6-IN-2(R)-84 is a potent and selective STAT6 inhibitor. It suppresses eotaxin-3 secretion and STAT6 tyrosine phosphorylation while inducing STAT6 reporter activity in cellular assays. This compound is a valuable research tool for studying STAT6-mediated pathways in allergic inflammation and asthma, applicable in both in vitro and in vivo experimental models.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1355594-85-2
• MW: 469.58
• Purity: 99.67% (May vary between batches)
• Formula: C₂₈H₃₁N₅O₂
• SMILES: CN1C(C=2C=C(C(N[C@@H](C(C)C)C)=O)N=C(C(NCCC3=CC=CC=N3)=O)C2)=CC=4C1=CC=CC4
• Target: STAT
• Solubility: DMSO:80 mg/mL (170.37 mM);10% DMSO+90% Corn Oil:3.3 mg/mL (7.03 mM)

Storage & Handling

• Storage: keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

STAT6

Compound Identifiers

PubChem CID

56950508