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STAT3-IN-49

SKU: orb3174709

Description

STAT3-IN-49 (compound B16) is a potent and selective inhibitor of STAT3. It binds to the SH2 domain of STAT3, blocking its phosphorylation and nuclear translocation. STAT3-IN-49 inhibits migration, invasion, and colony formation in triple-negative breast cancer (TNBC) cells. Additionally, it suppresses tumor growth in the MDA-MB-231 xenograft mouse model. STAT3-IN-49 is applicable for TNBC research.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

TargetSTAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information