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STAT3-IN-34

SKU: orb2665259

Description

STAT3-IN-34 is a potent small molecule inhibitor of STAT3, blocking its nuclear translocation and transcriptional activity. With an IC50 of 0.008 μM in HaCaT cell proliferation assays, it also reduces IL-17A expression and has demonstrated efficacy in an Imiquimod-induced mouse model of psoriasis.

Research Area

Cancer Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

MW368.41
FormulaC19H16N2O4S
TargetSTAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information