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STAT3-IN-1

SKU: orb1309061

Description

STAT3-IN-1 is a selective, orally bioavailable STAT3 inhibitor with IC50 values of 1.82 μM in HT29 and 2.14 μM in MDA-MB-231 cells. It promotes tumor cell apoptosis and is a valuable tool for studying STAT3-driven cancers in both cellular and animal models of oncology research.

Research Area

Cancer Biology, Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2059952-75-7
MW475.53
Purity98.13% (May vary between batches)
FormulaC28H29NO6
SMILESCOc1cc(OC)cc(\C=C\c2ccc(NC(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)cc2)c1
TargetSTAT,Apoptosis
SolubilityDMSO:125 mg/mL (262.86 mM)

Bioactivity

Target IC50
STAT3:1.82 μM (in HT29 cells)|STAT3:2.14 μM (in MDA-MB 231 cells)
In Vitro
STAT3-IN-1 induces tumor cells apoptosis in MDA-MB-231 cells

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Apoptosis, inhibit, Inhibitor, STAT, STAT3, STAT3 IN 1, STAT3 in HT29 cells, STAT3 in MDA-MB 231 cells, STAT3IN1, STAT-3-IN-1, STAT3-IN-1

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
1 ml x 10 mM (in DMSO)
$ 180.00
5 mg
$ 180.00
10 mg
$ 230.00
25 mg
$ 410.00
50 mg
$ 510.00
100 mg
$ 730.00
DispatchUsually dispatched within 5-10 working days
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