SSR180711 hydrochloride

SKU: orb1699236

Description

SSR180711 hydrochloride is a selective partial agonist of the Alpha7 nicotinic acetylcholine receptor. It is utilized in preclinical research to investigate cognitive function and neuroprotection, with applications in studies of Alzheimer's disease, schizophrenia, and related cognitive deficits using both in vitro and in vivo models.

Research Area

Neuroscience

Key Properties

• CAS Number: 446031-79-4
• MW: 361.66
• Purity: 99.77% (May vary between batches)
• Formula: C₁₄H₁₈BrClN₂O₂
• SMILES: Cl.Brc1ccc(OC(=O)N2CCN3CCC2CC3)cc1
• Target: AChR
• Solubility: DMSO:30 mg/mL (82.95 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.53 mM)

Bioactivity

• Target IC50:
  α7 nAChR (human):14 nM (Ki)|α7 nAChR (human):18 nM|α7 nAChR (rat):22 nM (Ki)|α7 nAChR (rat):30 nM

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

SSR180711, SSR-180711, SSR180711A, SSR-180711A, SSR-180711A HCl, SSR-180711C, SSR-180711C HCl, SSR 180711, SSR 180711 Hydrochloride, SR 180711, SR180711, SR-180711, SR-180711 HCl, α7 nAChR

Compound Identifiers

PubChem CID

9928899