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SRT 1720

SKU: orb1223634

Description

A potent, selective SIRT1 activator with EC1.5 of 0.16 uM; displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM); 1,000-fold more potent than resveratrol; improve insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity in obese mice model.

Images & Validation

Key Properties

CAS Number925434-55-5
MW469.5614
Purity>98% (HPLC)
FormulaC25H23N7OS
SMILESC1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5
TargetSirtuin
Solubility10 mM in DMSO

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SRT-1720 | SRT1720

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Protocol Information

SRT 1720 (orb1223634)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 100.00
10 mg
$ 140.00
25 mg
$ 250.00
50 mg
$ 440.00
100 mg
$ 620.00