(S,R,S)-AHPC-O-Ph-PEG1-NH2

SKU: orb1987756

Description

(S,R,S)-AHPC-O-Ph-PEG1-NH2 (VH032-O-Ph-PEG1-NH2) is a VHL-based E3 ligase ligand-linker conjugate used to construct PROTAC molecules. It serves as a key component in PROTAC EED degrader-1, a potent degrader (pKD 9.02) of the EED protein for targeted protein degradation research in biochemical and cellular studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2361117-24-8
• MW: 623.76
• Formula: C₃₂H₄₁N₅O₆S
• SMILES: Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COc2ccc(OCCN)cc2)C(C)(C)C)cc1
• Target: E3 Ligase Ligand-Linker Conjugates,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138693897