(S,R,S)-AHPC-Me dihydrochloride

SKU: orb1707973

Description

(S,R,S)-AHPC-Me dihydrochloride (VHL Ligand 2) is a key component for constructing VHL-based PROTAC degraders like ARV-771. This potent VHL-recruiting ligand enables the targeted degradation of proteins, such as BET proteins, which has been demonstrated in cellular studies for castration-resistant prostate cancer research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• MW: 517.51
• Formula: C₂₃H₃₄Cl₂N₄O₃S
• SMILES: N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O.Cl.Cl
• Target: Others,Ligands for E3 Ligase,E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137319712