(S,R,S)-AHPC-Me-C10-NH2 hydrochloride

SKU: orb1307296

Description

This compound is a VHL-based E3 ligase ligand-linker conjugate, synthesized for research use. It serves as a key component in the construction of PROTACs and other bifunctional molecules for targeted protein degradation studies in both cellular and in vivo models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2471970-07-5
• Purity: 97.80%
• Formula: C₃₄H₅₃N₅O₄S.xHCl
• Target: Ligands for E3 Ligase

Bioactivity

• In Vitro:
  PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Storage & Handling

• Storage: Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

VHL, (S,R,S) AHPC Me C10 NH2 hydrochloride, (S,R,S)AHPCMeC10NH2 hydrochloride, (S,R,S)-AHPC-Me-C-10-NH2 hydrochloride, AHPC-Me-C10-NH2 Hydrochloride, Ligand for E3 Ligase, LigandforE3Ligase

Compound Identifiers

PubChem CID

170911243