(S,R,S)-AHPC-Me-C10-Br

SKU: orb1987758

Description

This chemically synthesized PROTAC ligand-linker conjugate incorporates an MS432-based MEK1/2 inhibitor linked to a VHL E3 ligase binder. It serves as a key component for constructing bifunctional degraders to probe MEK protein function and degradation pathways in both cellular and in vivo research contexts.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2836297-55-1
• MW: 691.76
• Formula: C₃₄H₅₁BrN₄O₄S
• SMILES: O=C(N[C@@H](C)C1=CC=C(C=C1)C2=C(N=CS2)C)[C@H]3N(C[C@@H](C3)O)C([C@@H](NC(CCCCCCCCCCBr)=O)C(C)(C)C)=O
• Target: Others
• Solubility: DMSO:80 mg/mL (115.65 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(S,R,S) AHPC Me C10 Br, (S,R,S)AHPCMeC10Br, (S,R,S)-AHPC-Me-C-10-Br, AHPC-Me-C10-Br

Compound Identifiers

PubChem CID

145925668