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SR17018

SKU: orb1223188

Description

SR17018 is an mu-opioid-receptor (MOR) agonist with an EC50 of 97 nM.

Images & Validation

Key Properties

CAS Number2134602-45-0
MW410.72
Purity>98% (HPLC)
FormulaC19H18Cl3N3O
SMILESClc3cc4NC(=O)N(C2CCN(Cc1ccc(Cl)cc1)CC2)c4cc3Cl
TargetCETP
SolubilityDMSO : 6.4 mg/mL. 15.58 mM;

Bioactivity

In Vitro
SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM. SR17018 shows no obvious effect on inducing βarrestin2 recruitment to the MOR at below 10 μM. SR17018 promotes signaling through G proteins or βarrestin2.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

SR17018 | SR-17018 | SR 17018

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Protocol Information

SR17018 (orb1223188)

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500 mg
5 mg
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200 mg
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