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SR-717 free acid

SR-717 free acid

Catalog Number: orb1690959

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Catalog Numberorb1690959
CategorySmall Molecules
DescriptionSR-717 free acid
Purity98.00%
MW345.266
Biological ActivitySR-717 free acid is a stable cGAMP mimetic and a non-nucleotide STING agonist. It exhibits antitumor activity with EC50 values of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.
CAS Number[2375420-34-9]
FormulaC15H9F2N5O3
SMILESOC(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccnc1
Storage-20°C
NoteFor research use only