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Catalog Number | orb1690959 |
---|---|
Category | Small Molecules |
Description | SR-717 free acid |
Purity | 98.00% |
MW | 345.266 |
Biological Activity | SR-717 free acid is a stable cGAMP mimetic and a non-nucleotide STING agonist. It exhibits antitumor activity with EC50 values of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. |
CAS Number | [2375420-34-9] |
Formula | C15H9F2N5O3 |
SMILES | OC(=O)c1cc(F)c(F)cc1NC(=O)c1ccc(nn1)-n1ccnc1 |
Storage | -20°C |
Note | For research use only |