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SR 1903

SKU: orb1694444

Description

SR 1903 is a dual modulator acting as an inverse agonist of RORγ and an agonist of LXR, with additional binding to PPARγ. It suppresses pro-inflammatory pathways in vitro and demonstrates efficacy in mouse models of arthritis and obesity by improving metabolic parameters and reducing disease severity.

Research Area

Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number1414248-06-8
MW523.51
FormulaC27H27F6N3O
SMILESCC1=C(C2=CC=C(C(C(F)(F)F)(C(F)(F)F)O)C=C2)C=CC(CN3CCN(CC=4C=CN=CC4)CC3)=C1
TargetOthers,Liver X Receptor,ROR,PPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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SR 1903 (orb1694444)

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