SR 12460

SKU: orb1692875

Description

SR 12460 is a small molecule that acts as an NBD mimetic, disrupting the IKKβ/NEMO interaction to inhibit NF-κB activation triggered by TNF-α or LPS. It has demonstrated efficacy in cellular assays and reduces acute pulmonary inflammation in mouse models, making it a useful research tool for studying inflammatory signaling pathways.

Key Properties

• CAS Number: 2055101-66-9
• MW: 325.74
• Formula: C₁₅H₁₄ClF₂N₃O
• SMILES: O=C(NC1=NC=C(Cl)C=C1)CNCCC=2C=C(F)C=C(F)C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

124117357