SPI-05

SKU: orb3136363

Description

SPI-05 is a non-competitive inhibitor of SUMO-specific proteases (SENP1/2) with an IC50 of 60 μM. It has potential applications in cancer research, particularly in the study of prostate cancer with SENP1 overexpression and solid tumors driven by hypoxia.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 5463-64-9
• MW: 678.74
• Formula: C₃₄H₂₆N₆O₆S₂
• SMILES: O=S(=O)(O)C1=CC(N=NC2=CC=C(N)C=3C=CC=CC23)=CC=C1C=CC4=CC=C(N=NC5=CC=C(N)C=6C=CC=CC56)C=C4S(=O)(=O)O
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

E1/E2/E3 Enzyme