SPI-001

SKU: orb2663677

Description

SPI-001 is a potent and selective PPM1D phosphatase inhibitor (IC50=0.48 µM) with demonstrated anticancer activity. It enhances p53 phosphorylation and induces apoptosis in PPM1D-overexpressing breast cancer cells, supporting its use in oncology research for both in vitro and in vivo mechanistic studies.

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 1220996-46-2
• MW: 540.97
• Formula: C₃₀H₆₀O₄Si₂
• SMILES: C[C@@]12[C@]([C@@H](O[Si](C(C)(C)C)(C)C)C[C@]3([C@]1(C[C@@H](C)C[C@H]3O[Si](CC)(CC)CC)[H])[H])([C@@](CO)(C)C[C@H](O)C2)[H]
• Target: MDM-2/p53,Apoptosis,Phosphatase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

45280035