Spebrutinib besylate

SKU: orb1707621

Description

Spebrutinib besylate (CC-292) is a potent, covalent inhibitor of Bruton's tyrosine kinase (Btk) with an IC50 below 0.5 nM. It is widely used in biochemical and cellular research to investigate Btk signaling in autoimmune disorders and B-cell malignancies, with applications in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1360053-81-1
MW	581.62
Formula	C₂₈H₂₈FN₅O₆S
SMILES	O=C(C=C)NC1=CC=CC(=C1)NC2=NC(=NC=C2F)NC3=CC=C(OCCOC)C=C3.O=S(=O)(O)C=1C=CC=CC1
Target	BTK

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

74892828 ↗

Key Properties

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No computed properties available.

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