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| Catalog Number | orb1987730 |
|---|---|
| Category | Small Molecules |
| Description | SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy. |
| Target | Drug-Linker Conjugates for ADC |
| MW | 995.59 |
| CAS Number | 1626359-62-3 |
| Formula | C46H63ClN4O14S2 |
| SMILES | [H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C |
| Storage | -20°C |
| Note | For research use only |
ELISA, FA, FACS, In vivo | |
Human | |
Human | |
Monoclonal | |
Unconjugated |
ELISA, FA, FACS, In vivo | |
Human | |
Chimeric | |
Monoclonal | |
Unconjugated |
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(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)