SP-A (196-215) (human) TFA

SKU: orb1980018

Description

This synthetic peptide, corresponding to residues 196-215 of human Surfactant Protein A, modulates immune responses by suppressing LPS-induced TNF-α release in dendritic cells and enhancing bacterial phagocytosis. In vivo studies demonstrate its therapeutic potential, reducing infection severity and bacterial load in murine models of Pseudomonas aeruginosa pneumonia.

Key Properties

• MW: 2397.47
• Formula: C₁₀₇H₁₄₅N₂₉O₃₅.XCF₃COOH
• SMILES: [H]NCC(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(NCC(N[C@]([C@@H](C)O)([H])C(N1CCC[C@H]1C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@]([C@@H](C)O)([H])C(N[C@@H](CC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)CC3=CNC4=C3C=CC=C4)=O)=O)=O)CC5=CC=C(O)C=C5)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)CC6=CC=C(O)C=C6)=O)=O)CC7=CC=CC=C7)=O)CC(O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361384